oral pathology

Oral pathology reference: Cases 27–30

Jan. 23, 2025
These four cases represent pathology you may encounter in your practice—from a soft, exophytic, dome-like lesion to fire-engine red gingival tissue. Use these clinical presentations and diagnoses as a reference tool.
Vicki Cheeseman, Associate Editor

It’s time for another roundup of oral pathology cases to help you sharpen your diagnostic skills. Here are four cases from your colleagues that you can study, save, and use as a reference as you diagnose future cases from your clinical exams.

If you have recently encountered a pathology case in your practice, we encourage you to share it with us. One of the best sources of learning is peer-to-peer. Email your details to Bethany Montoya, editorial director of Clinical Insights newsletter, at [email protected]. We look forward to featuring you!

Stay tuned for more pathology content from DentistryIQ.

Patient: 6-year-old male

  • 7 mm-plus soft, exophytic, dome-like lesion
  • Normal lip color
  • Fluid-filled with a slightly red base
  • No pain, but patient was having a hard time eating due to position and size of lesion
  • Patient had habit of biting his lip

A soft, exophytic, dome-like lesion

Patient: 66-year-old female

  • 9 mm x 6 mm white, corrugated, irregular-bordered lesion
  • Lesion located in upper right vestibular area
  • Not tender to touch or palpation
  • Not able to be removed or scraped off
  • Large leukoplakic patch over erythematous tissue

Two weeks later …

  • Lesion extended back toward first molar to mucolabial fold area

Lesion’s dysplastic nature gives rise to concern

Patient: 2-year-old male

  • Lump on right side of neck
  • Ulcer-like lesions on buccal oral mucosa
  • PCP diagnosed patient with hand, foot and mouth disease

A week later …

  • Fire-engine red gingival tissue
  • Manifestation of numerous perioral lesions
  • Fever, loss of appetite, myalgia
  • No lesions on hands or feet

Fire-engine red gingival tissue with perioral lesions

Patient: 22-year-old female

  • Patient referred to oral surgeon for removal of wisdom teeth
  • Following that, all contact with patient was lost

Seven years later …

  • Large radiolucent lesion
  • Significant bone destruction in mandible
  • Inflamed tissue
  • Tender to palpation

Dangerous lesion if left untreated

Editor’s note: This article first appeared in Clinical Insights newsletter, a publication of the Endeavor Business Media Dental Group. Read more articles and subscribe.

About the Author

Vicki Cheeseman | Associate Editor

Vicki Cheeseman is an associate editor in Endeavor Business Media’s Dental Group. She edits for Dental Economics, RDH, DentistryIQ, and Perio-Implant Advisory. She has a BS in mathematics and a minor in computer science. Early on she traded numbers for words and has been happy ever since. Vicki began her career with Dental Economics in 1987 and has been fascinated with how much media production has changed through the years, yet editorial integrity remains the goal. In her spare time, you’ll find her curled up with a book—editor by day, reader always.